Since 2022, numerous clinical trials investigating psychedelic medicines for treating conditions like depression have shown promising outcomes. Researchers are exploring these substances' potential to alleviate symptoms where traditional treatments often fall short.

These trials highlight a renewed interest in psychedelics, suggesting they could revolutionize mental health treatment. The results

https://www.bbc.com/news/articles/ckg936l88e7o?at_medium=RSS&at_campaign=rss

Should the NHS use magic mushrooms to treat mental health?

Many clinical trials to test the use of psychedelic medicines for conditions such as depression have been underway since 2022 - with surprising results

^{Pallab Ghosh (BBC News)}

Woody Guthrie Creates a Doodle-Filled List of 33 New Year’s Resolutions (1943): Beat Fascism, Write a Song a Day, and Keep the Hoping Machine Running

https://www.openculture.com/2026/01/woody-guthrie-creates-a-doodle-filled-list-of-33-new-years-resolutions-1943.html

#newyear

TIL about NETosis, an immune response where your cells use their DNA to form a net to capture pathogens like bacteria, viruses and parasites

https://www.frontiersin.org/research-topics/826/netosis-at-the-intersection-of-cell-biology-microbiology-and-immunology/magazine
#til #todayilearned
https://www.reddit.com/r/todayilearned/comments/1q1ykvq/til_about_netosis_an_immune_response_where_your/

What is clear sign that a country is failing drastically?

"The U.S. has over 900 billionaires"

Okay, that does it..

🚨 The first preliminary analysis from the Japan Meteorological Agency highlights 2025 as the third warmest year on record globally (since at least 1891 in this data).

Additional climate rankings will be released later for other datasets.

Graph and methods by https://ds.data.jma.go.jp/tcc/tcc/products/gwp/temp/ann_wld.html

NEW ARTICLE // Tacoma Turns to Builder Impact Fees to Bolster Transportation Funding

Article by Ryan Packer via @urbanistorg // 🔗 https://www.theurbanist.org/2026/01/02/tacoma-turns-to-builder-impact-fees-to-bolster-transportation-funding/
https://www.theurbanist.org/2026/01/02/tacoma-turns-to-builder-impact-fees-to-bolster-transportation-funding/?fsp_sid=1923

Wow.. This is timely, i finished @pluralistic 's book #enshitification yesterday and today this pops up on my masto feed. Pretty shameful. I'm not sure if there's really a chance it'll get taken down. so i'll use my comically long character limit for good here.

Originally posted at https://www.reddit.com/r/confession/s/P3zG0fI7sr

"I’m posting this from a library Wi-Fi on a burner laptop because I am technically under a massive NDA. I don’t care anymore. I put in my two weeks yesterday and honestly, I hope they sue me. I’ve been sitting on this for about eight months, just watching the code getting pushed to production, and I can’t sleep at night knowing I helped build this machine.

You guys always suspect the algorithms are rigged against you, but the reality is actually so much more depressing than the conspiracy theories. I’m a backend engineer. I sit in the weekly sprint planning meetings where Product Managers (PMs) discuss how to squeeze another 0.4% margin out of "human assets" (that’s literally what they call drivers in the database schemas). They talk about these people like they are resource nodes in a video game, not fathers and mothers trying to pay rent.

First off, the "Priority Delivery" is a total scam. It was pitched to us as a "psychological value add." Like I said in the title, when you pay that extra $2.99, it changes a boolean flag in the order JSON, but the dispatch logic literally ignores it. It does nothing to speed you up.

We actually ran an A/B test last year where we didn't speed up the priority orders, we just purposefully delayed non-priority orders by 5 to 10 minutes to make the Priority ones "feel" faster by comparison. Management loved the results. We generated millions in pure profit just by making the standard service worse, not by making the premium service better.

But the thing that actually makes me sick—and the main reason I’m quitting—is the "Desperation Score." We have a hidden metric for drivers that tracks how desperate they are for cash based on their acceptance behavior.

If a driver usually logs on at 10 PM and accepts every garbage $3 order instantly without hesitation, the algo tags them as "High Desperation." Once they are tagged, the system then deliberately stops showing them high-paying orders. The logic is: "Why pay this guy $15 for a run when we know he’s desperate enough to do it for $6?" We save the good tips for the "casual" drivers to hook them in and gamify their experience, while the full-timers get grinded into dust.

Then there is the "Benefit Fee." You’ve probably seen that $1.50 "Regulatory Response Fee" or "Driver Benefits Fee" that appeared on your bill after the recent labor laws passed. The wording is designed to make you feel like you're helping the worker.

In reality, that money goes straight to a corporate slush fund used to lobby against driver unions. We have a specific internal cost center for "Policy Defense," and that fee feeds directly into it. You are literally paying for the high-end lawyers that are fighting to keep your delivery guy homeless.

And regarding tips, we're essentially doing Tip Theft 2.0. We don't "steal" them legally anymore because we got sued for that. Instead, we use predictive modeling to dynamically lower the base pay.

If the algo predicts you are a "high tipper" and you’ll likely drop $10, it offers the driver a measly $2 base pay. If you tip $0, it offers them $8 base pay just to get the food moved. The result is that your generosity isn't rewarding the driver; it’s subsidizing us. You’re paying their wage so we don't have to." https://social.lansky.name/@hn50/115823935915289539

I'd like you to know some numbers.

340.
That's the number of brand new billionaires we made in 2025. Roughly one a day and more than any other year.

9 million.
That's the number of people who died of hunger in 2025. Over 24,000 every single day for an entire year.

40 billion.
That's the number of dollars it would cost to end world hunger. Not to alleviate it. Not to lessen it. To eradicate it.

11.
That's the percentage tax we would have needed to impose on ONLY new wealth on ONLY billionaires in ONLY 2025 in order to eradicate world hunger. Eleven percent. That's all. Compared to the vast coffers of wealth they've already accumulated that's a rounding error.

Eat the rich. Tax them now.